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recent selections:

GPR68 Senses Flow and Is Essential for Vascular Physiology.

Xu J, Mathur J, Vessières E, Hammack S, Nonomura K, Favre J, Grimaud L, Petrus M, Francisco A, Li J, Lee V, Xiang FL, Mainquist JK, Cahalan SM, Orth AP, Walker JR, Ma S, Lukacs V, Bordone L, Bandell M, Laffitte B, Xu Y, Chien S, Henrion D, Patapoutian A.

Cell. 2018 Apr 19;173(3):762-775.e16. doi: 10.1016/j.cell.2018.03.076.

 

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.

Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, Bandell M, Schmedt C, Wengelnik K, Su AI, Honore E, Winzeler EA, Andersen KG, Patapoutian A.

Cell. 2018 Apr 5;173(2):443-455.e12. doi: 10.1016/j.cell.2018.02.047. Epub 2018 Mar 22.

 

Structure of the mechanically activated ion channel Piezo1.

Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB.

Nature. 2018 Feb 22;554(7693):481-486. doi: 10.1038/nature25453. Epub 2017 Dec 20.

 

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.

Syeda R, Qiu Z, Dubin AE, Murthy SE, Florendo MN, Mason DE, Mathur J, Cahalan SM, Peters EC, Montal M, Patapoutian A.

Cell. 2016 Jan 28;164(3):499-511. doi: 10.1016/j.cell.2015.12.031.

 

Piezo2 is the principal mechanotransduction channel for proprioception.

Woo SH, Lukacs V, de Nooij JC, Zaytseva D, Criddle CR, Francisco A, Jessell TM, Wilkinson KA, Patapoutian A.

Nat Neurosci. 2015 Dec;18(12):1756-62. doi: 10.1038/nn.4162. Epub 2015 Nov 9.

 

Piezo2 is the major transducer of mechanical forces for touch sensation in mice.

Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A.

Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980.